SAN FRANCISCO -- Matt Cains winless drought is over, even though the Giants three-time All-Star pitcher is still struggling with some of his mechanics. After nearly seven weeks of frustration, Cain isnt about to complain. Buster Posey hit a go-ahead double as part of a three-run fifth inning and San Francisco held on to beat the Miami Marlins 6-4 on Thursday night. Cain (1-3) earned his first win of the season despite another shaky outing at AT&T Park. The former San Francisco ace gave up two home runs and allowed all the Marlins scoring in the first three innings before settling down to pitch into the eighth. "He didnt cave in," Giants manager Bruce Bochy said. "He gave up four runs in the first three innings and here he is in the eighth. It says a lot about him. Good for him. Its got to be a good feeling." Cain hadnt won since Aug. 17, 2013 -- a string of 11 consecutive starts. It looked like the drought might continue after Cain was nearly knocked out of the game in the third inning, but he stuck around long enough to get the win in his second outing since slicing the index finger on his right hand. After giving up two home runs to the first seven batters he faced, Cain settled down to allowed six hits over 7 2-3 uneven innings. He struck out seven and walked three. "I made some bad pitches and those guys really capitalized on it," Cain said. "I was making good pitches other than that. I just needed to eliminate the big one that kept costing me." Mike Morse homered for the second consecutive game and drove in three runs while Hunter Pence added three hits and scored twice for the Giants, who trailed by three runs before rallying to bail out Cain. Garrett Jones hit his sixth home run for Miami. The Marlins had won 12 of their last 15 games at the Giants waterfront ballpark and were comfortably ahead 4-1 before San Franciscos comeback. "We swung the bats great in the first three innings," Miami manager Mike Redmond said. "We have to do a better job of shutting them down after we score. We have to do a better job of executing our pitches and shutting them down." Morse, who finished with three hits, cut the gap to 4-3 when he hit a two-run home run off Miami starter Nathan Eovaldi (2-2) in the third. The Giants took the lead for good in the fifth after Angel Pagan drew a leadoff walk and Pence singled. Posey followed with his towering drive to right-centre. Morse added an RBI single. Jeremy Affeldt retired one batter and Sergio Romo worked the ninth for his 14th save. Miami couldnt capitalize off the quick start and was held scoreless over the final six innings. The Marlins announced before the game that ace Jose Fernandez will have Tommy John surgery Friday, ending the season for the reigning NL Rookie of the Year. "Our focus is to get him back," Redmond said. "Im glad hes having it done and starting his recovery process. Obviously its a big blow for us." Giancarlo Stanton singled in the fifth to extend his 17-game hitting streak but the Marlins dropped to 2-6 on their 11-game road trip. Cain fell behind early after giving up a solo home run to Derek Dietrich with one out in the first. Miami added two runs in the second on Jones two-run homer, then made it 4-1 on Casey McGehees RBI double in the third. Eovaldi gave up an RBI groundout to Brandon Hicks in the second then retired four straight following Morses home run until the Giants broke the game open in the fifth. Eovaldi allowed nine hits and six runs over 4 1-3 innings. NOTES: Pablo Sandoval went 1 for 4 in his return to the Giants lineup after leaving Sundays win over Atlanta with a sore toe. ... RHP Anthony DeSclafani, who made his major league debut Sunday in Fernandezs place, will remain in the Marlins rotation for now. ... 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